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Kevin Harvatine
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Kevin Harvatine

  • Assistant Professor of Nutritional Physiology
301 Henning Building
University Park , PA 16802
E-mail:

Office Phone: (814) 865-6334

Education

  1. Post-doctorate, Cornell University, 2008
  2. Ph.D., Cornell University, 2008
  3. M.S., Michigan State University, 2003
  4. B.S., Penn State, 2001

Research and Teaching Interests

Traditionally nutrients were simply considered substrate for metabolism and nutritionists calculated the energy and protein delivered by different feedstuffs. However, some absorbed nutrients are bioactive and have the ability to modify physiological and metabolic processes. Nutritional modification of physiological processes has the potential to increase dairy production efficiency and profitability, but dietary associative effects in the rumen are difficult to predict and the nutrient-physiology interactions are complex. Recent advances in molecular biology provide powerful tools to investigate bioactive nutrients and provide insight into regulation of metabolism. This type of research has recently been called nutrigenomics and the study of nutrient-gene interactions is a significant part of the field.

Dr. Harvatine’s research integrates traditional ruminant nutrition and modern molecular biology approaches to investigate the regulation of metabolism and develop dietary intervention strategies to improve dairy production. Research approaches utilize bovine and mouse in vivo experiments and cell culture systems. Specific research objectives include investigation of dietary factors that modify ruminal fatty acid biohydrogenation, regulation of synthesis of milk components, and basic regulation of lipid synthesis with the continual goal of developing feeding strategies to improve the efficiency and performance of dairy cows.

 

 

Selected Publications

  • Harvatine, K.J., J.L. Capper, Y.R. Boisclair, and D.E. Bauman. Recent advances in milk fat depression. Accepted. ANIMAL.
  • Bauman, D.E., J.W. Perfield II, K.J. Harvatine, and L.H. Baumgard. 2008. Regulation of fat synthesis by CLA: Lactation and the ruminant model. J. Nutr. 138(2):403-9
  • Bradford, B.J.*, K.J. Harvatine*, and M.S. Allen. 2007. Dietary unsaturated fatty acids increase plasma GLP-1 and CCK and pre-meal ghrelin in lactating dairy cows. J. Dairy Sci. 91:1443-50. *Authors contributed equally to work
  • Lock, A.L., C. Tyburczy, D.A. Dwyer, K.J. Harvatine, F. Destaillats, Z. Mouloungui, L. Candy, and D.E. Bauman. 2007. Trans-10 octadecenoic acid does not reduce milk fat synthesis in dairy cows. J. Nutr. 137(1):71-6
  • Harvatine, K.J., and D.E. Bauman. 2006. SREBP1 and thyroid hormone responsive spot 14 (S14) are involved in the regulation of bovine mammary lipid synthesis during Pg. 3
  • Kevin J. Harvatine, diet-induced milk fat depression and treatment with CLA. J. Nutr. 136(10):2468- 74.
  • Harvatine, K.J., and M.S. Allen. 2006. Effects of fatty acid supplements on fractional kinetics of ruminal fatty acid biohydrogenation. J. Nutr. 136:677-85.
  • Harvatine, K.J., and M.S. Allen. 2006. Effects of fatty acid supplements on milk yield and energy balance of lactating dairy cows. J. Dairy Sci. 89:1081-91.
  • Harvatine, K.J., and M.S. Allen. 2006. Effects of fatty acid supplements on ruminal and total tract nutrient digestion in lactating dairy cows. J. Dairy Sci. 89:1092-103.
  • Harvatine, K.J., and M.S. Allen. 2006. Effects of fatty acid supplements on feed intake, and feeding and chewing behavior of lactating dairy cows. J. Dairy Sci. 89:1104- 12.
  • Harvatine, K.J., and M.S. Allen. 2005. The effect of production level on feed intake, milk yield and endocrine response to two fatty acid supplements in lactating cows. J. Dairy Sci. 88:4018-27.
  • Allen, M.S., B.J. Bradford, and K.J. Harvatine. 2005. The cow as a model to study food intake regulation. Ann. Rev. Nutr. 25:523-47.
  • Harvatine, K.J., and D.E. Bauman. 2007. Recent advances in milk fat depression: 1. Time course of milk fat depression and 2. Adipose tissue lipogenesis during milk fat depression. Proc. Cornell Nutr. Conf. Feed Manuf., Cornell Univ., pg 135-142.
  • Bauman, D.E., T. Hinrichsen, C. Tyburczy, K.J. Harvatine, and A.L. Lock. 2006. Update on milk fat: Identification of rumen biohydrogenation intermediates that inhibit synthesis. Proc. Cornell Nutr. Conf. Feed Manuf., Cornell Univ., pg. 59-65
  • Harvatine, K.J., and D.E. Bauman. 2006. Update on milk fat: Cellular mechanism for inhibition of milk fat synthesis by rumen biohydrogenation intermediates. Proc. Cornell Nutr. Conf. Feed Manuf., Cornell Univ., pg. 67-73.
  • Lock, A.L., T.R. Overton, K.J. Harvatine, J. Geisy, and D.E. Bauman. 2006. Milk fat depression: Impact of dietary components and their interaction during rumen fermentation. Proc. Cornell Nutr. Conf. Feed Manuf., Cornell Univ., pg. 75-85.
  • Lock, A.L., K.J. Harvatine, and D.E. Bauman. 2006. Concepts in fat and fatty acid digestion in ruminants. Intermountain Nutrition Conference, Salt Lake City, UT.
  • Lock, A. L., K. J. Harvatine, I. R. Ipharraguerre, M. E. Van Amburgh, J. K. Drackley, and D. E. Bauman. 2006. Dynamics of ruminant fat digestion: Part 2. Feedstuffs, April 17, pg. 16-17.
  • Lock, A. L., K. J. Harvatine, I. R. Ipharraguerre, M. E. Van Amburgh, J. K. Drackley, and D. E. Bauman. 2006. Dynamics of ruminant fat digestion: Part 1. Feedstuffs, February 13, pg. 16-17.
  • Lock, A.L., K.J. Harvatine, I.R. Ipharraguerre, M.E. Van Amburgh, J.K. Drackley, and D.E. Bauman. 2005. The dynamics of fat digestion in lactating dairy cows: What does the literature tell us? Proc. Cornell Nutr. Conf. Feed Manuf., Cornell Univ., pg. 83-94.